BDBM50385121 CHEMBL2036311
SMILES: O[C@@H](Cc1cccc(c1)-c1ccc2[nH]ccc2c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O
InChI Key: InChIKey=NUXMYQHRAUGVMF-RSURJUNSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50385121 (CHEMBL2036311) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50385121 (CHEMBL2036311) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50385121 (CHEMBL2036311) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50385121 (CHEMBL2036311) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Rattus norvegicus) | BDBM50385121 (CHEMBL2036311) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 85 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Agonist activity at rat EP4 receptor expressed in CHO cells assessed as cAMP production after 10 mins by radioimmunoassay | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair |