BDBM50385145 CHEMBL2035654
SMILES: Oc1ccc2ccccc2c1-c1ccc(cc1)C(=O)NCCN1CCOCC1
InChI Key: InChIKey=MQRMUEVIQDAAEW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostaglandin D Synthase (Homo sapiens (Human)) | BDBM50385145 (CHEMBL2035654) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 662 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur... | Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |