BDBM50385372 CHEMBL2036372

SMILES: CC(C)Cc1ccc(Cc2nc3ccccc3n2Cc2ccccc2Cl)cc1

InChI Key: InChIKey=KIOGDRBSWIJQHT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50385372 (CHEMBL2036372) Show SMILES CC(C)Cc1ccc(Cc2nc3ccccc3n2Cc2ccccc2Cl)cc1 Show InChI InChI=1S/C25H25ClN2/c1-18(2)15-19-11-13-20(14-12-19)16-25-27-23-9-5-6-10-24(23)28(25)17-21-7-3-4-8-22(21)26/h3-14,18H,15-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Gazi University Curated by ChEMBL					Assay Description Inhibition of FLAP in A23187-stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 10 mins				Bioorg Med Chem 20: 3728-41 (2012) Article DOI: 10.1016/j.bmc.2012.04.048 BindingDB Entry DOI: 10.7270/Q26H4JFM
					More data for this Ligand-Target Pair