null

SMILES: Clc1ccc(NC(=O)N2CCN(C[C@H]3CN(CCO3)C3CC3)CC2)cc1Cl

InChI Key: InChIKey=IXACLKNSEGSKGF-INIZCTEOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50385457 (CHEMBL2036774) Show SMILES Clc1ccc(NC(=O)N2CCN(C[C@H]3CN(CCO3)C3CC3)CC2)cc1Cl |r| Show InChI InChI=1S/C19H26Cl2N4O2/c20-17-4-1-14(11-18(17)21)22-19(26)24-7-5-23(6-8-24)12-16-13-25(9-10-27-16)15-2-3-15/h1,4,11,15-16H,2-3,5-10,12-13H2,(H,22,26)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 22: 3895-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.118 BindingDB Entry DOI: 10.7270/Q2PG1SRD
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50385457 (CHEMBL2036774) Show SMILES Clc1ccc(NC(=O)N2CCN(C[C@H]3CN(CCO3)C3CC3)CC2)cc1Cl |r| Show InChI InChI=1S/C19H26Cl2N4O2/c20-17-4-1-14(11-18(17)21)22-19(26)24-7-5-23(6-8-24)12-16-13-25(9-10-27-16)15-2-3-15/h1,4,11,15-16H,2-3,5-10,12-13H2,(H,22,26)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assay				Bioorg Med Chem Lett 22: 3895-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.118 BindingDB Entry DOI: 10.7270/Q2PG1SRD
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50385457 (CHEMBL2036774) Show SMILES Clc1ccc(NC(=O)N2CCN(C[C@H]3CN(CCO3)C3CC3)CC2)cc1Cl |r| Show InChI InChI=1S/C19H26Cl2N4O2/c20-17-4-1-14(11-18(17)21)22-19(26)24-7-5-23(6-8-24)12-16-13-25(9-10-27-16)15-2-3-15/h1,4,11,15-16H,2-3,5-10,12-13H2,(H,22,26)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysis				Bioorg Med Chem Lett 22: 3895-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.118 BindingDB Entry DOI: 10.7270/Q2PG1SRD
					More data for this Ligand-Target Pair