BDBM50385906 CHEMBL2041597

SMILES: COc1cc(COC(=O)c2ccc(o2)-c2ccccc2C(F)(F)F)cc(OC)c1OC

InChI Key: InChIKey=HOVKCNXSFFJEQX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50385906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50385906 (CHEMBL2041597) Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2C(F)(F)F)cc(OC)c1OC Show InChI InChI=1S/C22H19F3O6/c1-27-18-10-13(11-19(28-2)20(18)29-3)12-30-21(26)17-9-8-16(31-17)14-6-4-5-7-15(14)22(23,24)25/h4-11H,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50385906 (CHEMBL2041597) Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2C(F)(F)F)cc(OC)c1OC Show InChI InChI=1S/C22H19F3O6/c1-27-18-10-13(11-19(28-2)20(18)29-3)12-30-21(26)17-9-8-16(31-17)14-6-4-5-7-15(14)22(23,24)25/h4-11H,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
					More data for this Ligand-Target Pair