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SMILES: O=C(CCCn1ccc(=O)[nH]c1=O)NCC(c1ccccc1)c1ccccc1

InChI Key: InChIKey=RAXILFXVFUAOGM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386596   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial


(Homo sapiens (Human))		BDBM50386596
PNG
(CHEMBL2048461)
Show SMILES O=C(CCCn1ccc(=O)[nH]c1=O)NCC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H23N3O3/c26-20(12-7-14-25-15-13-21(27)24-22(25)28)23-16-19(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-6,8-11,13,15,19H,7,12,14,16H2,(H,23,26)(H,24,27,28)
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KEGG

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysis

J Med Chem 55: 2960-9 (2012)


Article DOI: 10.1021/jm201627n
BindingDB Entry DOI: 10.7270/Q2WQ04VS
More data for this
Ligand-Target Pair