BDBM50386603 CHEMBL2046464

SMILES: OC([C@@H]1CCCN1C(=O)CCCn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=ZBQTYWZUWNJULN-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Homo sapiens (Human))	BDBM50386603 (CHEMBL2046464) Show SMILES OC([C@@H]1CCCN1C(=O)CCCn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H27N3O4/c29-22-15-18-27(24(31)26-22)16-8-14-23(30)28-17-7-13-21(28)25(32,19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-6,9-12,15,18,21,32H,7-8,13-14,16-17H2,(H,26,29,31)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysis				J Med Chem 55: 2960-9 (2012) Article DOI: 10.1021/jm201627n BindingDB Entry DOI: 10.7270/Q2WQ04VS
					More data for this Ligand-Target Pair