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SMILES: [O-][N+](=O)c1ccc(cc1)-n1nc(c2NS(=O)(=O)c3ccccc3-c12)-c1ccc(Cl)cc1

InChI Key: InChIKey=QNPCICNURAFUQC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386656   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Quinolone resistance protein NorA


(Staphylococcus aureus)		BDBM50386656
PNG
(CHEMBL2048632)
Show SMILES [O-][N+](=O)c1ccc(cc1)-n1nc(c2NS(=O)(=O)c3ccccc3-c12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H13ClN4O4S/c22-14-7-5-13(6-8-14)19-20-21(17-3-1-2-4-18(17)31(29,30)24-20)25(23-19)15-9-11-16(12-10-15)26(27)28/h1-12,24H
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Universit£ degli Studi di Perugia

Curated by ChEMBL


Assay Description
Inhibition of norA-mediated EtBr efflux in Staphylococcus aureus SA1199B overexpressing norA and expressing A116E GrlA mutation by fluorometry

J Med Chem 55: 3568-72 (2012)


Article DOI: 10.1021/jm201446h
BindingDB Entry DOI: 10.7270/Q2HD7WQ7
More data for this
Ligand-Target Pair