BDBM50387013 CHEMBL2049188

SMILES: CCCN(CCC)c1cccc2nc(Nc3c(C)cc(C)cc3C)c(C)nc12

InChI Key: InChIKey=RWYLUZYLNSDJGQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50387013 (CHEMBL2049188) Show SMILES CCCN(CCC)c1cccc2nc(Nc3c(C)cc(C)cc3C)c(C)nc12 Show InChI InChI=1S/C24H32N4/c1-7-12-28(13-8-2)21-11-9-10-20-23(21)25-19(6)24(26-20)27-22-17(4)14-16(3)15-18(22)5/h9-11,14-15H,7-8,12-13H2,1-6H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	563	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation preincu...				Bioorg Med Chem Lett 22: 4756-61 (2012) Article DOI: 10.1016/j.bmcl.2012.05.066 BindingDB Entry DOI: 10.7270/Q21837JW
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50387013 (CHEMBL2049188) Show SMILES CCCN(CCC)c1cccc2nc(Nc3c(C)cc(C)cc3C)c(C)nc12 Show InChI InChI=1S/C24H32N4/c1-7-12-28(13-8-2)21-11-9-10-20-23(21)25-19(6)24(26-20)27-22-17(4)14-16(3)15-18(22)5/h9-11,14-15H,7-8,12-13H2,1-6H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 4756-61 (2012) Article DOI: 10.1016/j.bmcl.2012.05.066 BindingDB Entry DOI: 10.7270/Q21837JW
					More data for this Ligand-Target Pair