BDBM50387033 CHEMBL2046533

SMILES: CCN(Cc1ccncc1)c1cccc2nc(Oc3c(OC)cc(COC)cc3OC)c(C)cc12

InChI Key: InChIKey=VSAGEAFBCQDAPJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50387033 (CHEMBL2046533) Show SMILES CCN(Cc1ccncc1)c1cccc2nc(Oc3c(OC)cc(COC)cc3OC)c(C)cc12 Show InChI InChI=1S/C28H31N3O4/c1-6-31(17-20-10-12-29-13-11-20)24-9-7-8-23-22(24)14-19(2)28(30-23)35-27-25(33-4)15-21(18-32-3)16-26(27)34-5/h7-16H,6,17-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 4756-61 (2012) Article DOI: 10.1016/j.bmcl.2012.05.066 BindingDB Entry DOI: 10.7270/Q21837JW
					More data for this Ligand-Target Pair