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BDBM50387485 CHEMBL2047485

SMILES: CCN1\C(=C\C=C\C2=[N+](CC)c3ccc4ccccc4c3C2(C)C)C(C)(C)c2c1ccc1ccccc21

InChI Key: InChIKey=QOCIGFHAVJNBSZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-arginine N-methyltransferase 1


(Homo sapiens (Human))		BDBM50387485
PNG
(CHEMBL2047485)
Show SMILES CCN1\C(=C\C=C\C2=[N+](CC)c3ccc4ccccc4c3C2(C)C)C(C)(C)c2c1ccc1ccccc21 |c:7|
Show InChI InChI=1S/C35H37N2/c1-7-36-28-22-20-24-14-9-11-16-26(24)32(28)34(3,4)30(36)18-13-19-31-35(5,6)33-27-17-12-10-15-25(27)21-23-29(33)37(31)8-2/h9-23H,7-8H2,1-6H3/q+1
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Article
PubMed
n/an/a 2.03E+4n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins ...

Eur J Med Chem 54: 647-59 (2012)


Article DOI: 10.1016/j.ejmech.2012.06.017
BindingDB Entry DOI: 10.7270/Q2XD12R6
More data for this
Ligand-Target Pair