BDBM50387571 CHEMBL2058046

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1ccccc1Oc1ccnc(Cl)n1)C(C)(C)C

InChI Key: InChIKey=SQYLNCWFANKRIL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50387571 (CHEMBL2058046) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1ccccc1Oc1ccnc(Cl)n1)C(C)(C)C Show InChI InChI=1S/C26H27ClN6O2/c1-17-9-11-19(12-10-17)33-22(15-21(32-33)26(2,3)4)30-25(34)29-16-18-7-5-6-8-20(18)35-23-13-14-28-24(27)31-23/h5-15H,16H2,1-4H3,(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant P38alpha-mediated ATF2 phosphorylation after 1 hr				Bioorg Med Chem Lett 22: 5118-22 (2012) Article DOI: 10.1016/j.bmcl.2012.05.095 BindingDB Entry DOI: 10.7270/Q2H41SH8
					More data for this Ligand-Target Pair