BDBM50387627 CHEMBL2058330

SMILES: CC[C@@H](COC)n1c2nccc(-c3ccc(Cl)cc3Cl)c2nc(C)c1=O

InChI Key: InChIKey=ZXVYJALWEMWQCF-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50387627 (CHEMBL2058330) Show SMILES CC[C@@H](COC)n1c2nccc(-c3ccc(Cl)cc3Cl)c2nc(C)c1=O |r| Show InChI InChI=1S/C19H19Cl2N3O2/c1-4-13(10-26-3)24-18-17(23-11(2)19(24)25)15(7-8-22-18)14-6-5-12(20)9-16(14)21/h5-9,13H,4,10H2,1-3H3/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Antagonist activity at rat CFR1R				Bioorg Med Chem Lett 22: 4986-9 (2012) Article DOI: 10.1016/j.bmcl.2012.06.034 BindingDB Entry DOI: 10.7270/Q23X87Q6
					More data for this Ligand-Target Pair