BDBM50387647 CHEMBL2057749

SMILES: Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC(CC3)n3c4ccccc4[nH]c3=O)ccc2c1

InChI Key: InChIKey=HWVQJBGFQNRSON-KAYWLYCHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50387647 (CHEMBL2057749) Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC(CC3)n3c4ccccc4[nH]c3=O)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C31H34FN5O2/c32-23-8-7-21-15-20(5-6-22(21)16-23)19-36-26-9-10-27(36)18-24(17-26)33-30(38)35-13-11-25(12-14-35)37-29-4-2-1-3-28(29)34-31(37)39/h1-8,15-16,24-27H,9-14,17-19H2,(H,33,38)(H,34,39)/t26-,27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR3				Bioorg Med Chem Lett 22: 4951-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.042 BindingDB Entry DOI: 10.7270/Q2057H06
					More data for this Ligand-Target Pair