BDBM50387717 CHEMBL2058623

SMILES: NC(=N)SCc1ccc(Cl)cc1Oc1ccc(F)cc1CSC(N)=N

InChI Key: InChIKey=VLGRWMXJHXFKOE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natural resistance-associated macrophage protein 1 (Homo sapiens (Human))	BDBM50387717 (CHEMBL2058623) Show SMILES NC(=N)SCc1ccc(Cl)cc1Oc1ccc(F)cc1CSC(N)=N Show InChI InChI=1S/C16H16ClFN4OS2/c17-11-2-1-9(7-24-15(19)20)14(6-11)23-13-4-3-12(18)5-10(13)8-25-16(21)22/h1-6H,7-8H2,(H3,19,20)(H3,21,22)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of NRAMP1 expressed in CHO cells				Bioorg Med Chem Lett 22: 5108-13 (2012) Article DOI: 10.1016/j.bmcl.2012.05.129 BindingDB Entry DOI: 10.7270/Q2QN67TM
					More data for this Ligand-Target Pair