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BDBM50387798 CHEMBL2057496

SMILES: Clc1ccc(nc1)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=SFXJJBKOXLHYOV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387798   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50387798
PNG
(CHEMBL2057496)
Show SMILES Clc1ccc(nc1)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C18H20ClN5O3S/c19-15-1-2-17(21-11-15)28(26,27)24-12-14(13-24)18(25)23-9-7-22(8-10-23)16-3-5-20-6-4-16/h1-6,11,14H,7-10,12-13H2
UniProtKB/SwissProt
UniProtKB/TrEMBL

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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...

Bioorg Med Chem Lett 22: 5035-40 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.018
BindingDB Entry DOI: 10.7270/Q2KW5H39
More data for this
Ligand-Target Pair