null

SMILES: Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(C)nc4ccccc34)cc2)c1C

InChI Key: InChIKey=MCGCJFJGNKEDPW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50387807 (CHEMBL2058367) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(C)nc4ccccc34)cc2)c1C Show InChI InChI=1S/C26H24N4O3S/c1-17-18(2)28-33-26(17)29-34(31,32)25-11-7-4-8-22(25)21-14-12-20(13-15-21)16-30-19(3)27-23-9-5-6-10-24(23)30/h4-15,29H,16H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cells				Bioorg Med Chem 20: 4661-7 (2012) Article DOI: 10.1016/j.bmc.2012.06.011 BindingDB Entry DOI: 10.7270/Q2G73FS6
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50387807 (CHEMBL2058367) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(C)nc4ccccc34)cc2)c1C Show InChI InChI=1S/C26H24N4O3S/c1-17-18(2)28-33-26(17)29-34(31,32)25-11-7-4-8-22(25)21-14-12-20(13-15-21)16-30-19(3)27-23-9-5-6-10-24(23)30/h4-15,29H,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex				Bioorg Med Chem 20: 4661-7 (2012) Article DOI: 10.1016/j.bmc.2012.06.011 BindingDB Entry DOI: 10.7270/Q2G73FS6
					More data for this Ligand-Target Pair