BDBM50387827 CHEMBL2058635

SMILES: CC1CCC(N1)=Nc1ccc(I)cc1Cl

InChI Key: InChIKey=KLIBTBNNCGHLPY-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50387827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Imidazoline I1 (RAT)	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Belgrade Curated by ChEMBL					Assay Description Displacement of [125I]PIC from Imidazoline-1 receptor in rat PC12 cell membrane incubated for 30 mins by gamma counting method				Bioorg Med Chem 24: 3174-83 (2016) BindingDB Entry DOI: 10.7270/Q2NZ89J3
					More data for this Ligand-Target Pair
Imidazoline I1 (RAT)	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma counting				J Med Chem 58: 878-87 (2015) Article DOI: 10.1021/jm501456p BindingDB Entry DOI: 10.7270/Q2R21333
					More data for this Ligand-Target Pair
Imidazoline I1 (RAT)	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.219	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]paraiodoclonidine from imidazoline I1 receptor in rat PC12 cells after 30 mins by gamma counter				Bioorg Med Chem 20: 4710-5 (2012) Article DOI: 10.1016/j.bmc.2012.06.008 BindingDB Entry DOI: 10.7270/Q26Q1Z9Q
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human alpha2 adrenoceptor expressed in CHO cell membranes after 60 mins				J Med Chem 58: 878-87 (2015) Article DOI: 10.1021/jm501456p BindingDB Entry DOI: 10.7270/Q2R21333
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]RX821001 from human alpha2A adrenoceptor expressed in CHO cells after 60 mins by gamma counter				Bioorg Med Chem 20: 4710-5 (2012) Article DOI: 10.1016/j.bmc.2012.06.008 BindingDB Entry DOI: 10.7270/Q26Q1Z9Q
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]RX821001 from human alpha2B adrenoceptor expressed in CHO cells after 60 mins by gamma counter				Bioorg Med Chem 20: 4710-5 (2012) Article DOI: 10.1016/j.bmc.2012.06.008 BindingDB Entry DOI: 10.7270/Q26Q1Z9Q
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50387827 (CHEMBL2058635) Show SMILES CC1CCC(N1)=Nc1ccc(I)cc1Cl |w:6.7| Show InChI InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]RX821001 from human alpha2C adrenoceptor expressed in CHO cells after 60 mins by gamma counter				Bioorg Med Chem 20: 4710-5 (2012) Article DOI: 10.1016/j.bmc.2012.06.008 BindingDB Entry DOI: 10.7270/Q26Q1Z9Q
					More data for this Ligand-Target Pair