BDBM50388071 CHEMBL2057862

SMILES: COc1cc(ccc1O)C(C)NC(=S)NCc1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=KMSGHHGTFHXTFR-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50388071 (CHEMBL2057862) Show SMILES COc1cc(ccc1O)C(C)NC(=S)NCc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C21H28N2O2S/c1-14(16-8-11-18(24)19(12-16)25-5)23-20(26)22-13-15-6-9-17(10-7-15)21(2,3)4/h6-12,14,24H,13H2,1-5H3,(H2,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	194	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from rat TRPV1 expressed in CHO cells				Bioorg Med Chem Lett 22: 5227-31 (2012) Article DOI: 10.1016/j.bmcl.2012.06.059 BindingDB Entry DOI: 10.7270/Q2NS0VZB
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50388071 (CHEMBL2057862) Show SMILES COc1cc(ccc1O)C(C)NC(=S)NCc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C21H28N2O2S/c1-14(16-8-11-18(24)19(12-16)25-5)23-20(26)22-13-15-6-9-17(10-7-15)21(2,3)4/h6-12,14,24H,13H2,1-5H3,(H2,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at rat TRPV1 expressed in CHO cells assessed as calcium uptake				Bioorg Med Chem Lett 22: 5227-31 (2012) Article DOI: 10.1016/j.bmcl.2012.06.059 BindingDB Entry DOI: 10.7270/Q2NS0VZB
					More data for this Ligand-Target Pair