Found 5 hits for monomerid = 50388782 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50388782
(CHEMBL2062564)Show SMILES CC(=O)Nc1ccc2cnn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 Show InChI InChI=1S/C19H16N8O/c1-11(28)23-15-3-2-12-9-21-26(16(12)6-15)18-7-17(24-14-4-5-14)27-19(25-18)13(8-20)10-22-27/h2-3,6-7,9-10,14,24H,4-5H2,1H3,(H,23,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of GSK3beta |
ACS Med Chem Lett 3: 278-283 (2012)
Article DOI: 10.1021/ml200257n
BindingDB Entry DOI: 10.7270/Q23N24GS |
More data for this
Ligand-Target Pair | |
Homeodomain-interacting protein kinase 2 (HIPK2)
(Homo sapiens (Human)) | BDBM50388782
(CHEMBL2062564)Show SMILES CC(=O)Nc1ccc2cnn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 Show InChI InChI=1S/C19H16N8O/c1-11(28)23-15-3-2-12-9-21-26(16(12)6-15)18-7-17(24-14-4-5-14)27-19(25-18)13(8-20)10-22-27/h2-3,6-7,9-10,14,24H,4-5H2,1H3,(H,23,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of HipK2 |
ACS Med Chem Lett 3: 278-283 (2012)
Article DOI: 10.1021/ml200257n
BindingDB Entry DOI: 10.7270/Q23N24GS |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha
(Homo sapiens (Human)) | BDBM50388782
(CHEMBL2062564)Show SMILES CC(=O)Nc1ccc2cnn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 Show InChI InChI=1S/C19H16N8O/c1-11(28)23-15-3-2-12-9-21-26(16(12)6-15)18-7-17(24-14-4-5-14)27-19(25-18)13(8-20)10-22-27/h2-3,6-7,9-10,14,24H,4-5H2,1H3,(H,23,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ... |
ACS Med Chem Lett 3: 278-283 (2012)
Article DOI: 10.1021/ml200257n
BindingDB Entry DOI: 10.7270/Q23N24GS |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50388782
(CHEMBL2062564)Show SMILES CC(=O)Nc1ccc2cnn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 Show InChI InChI=1S/C19H16N8O/c1-11(28)23-15-3-2-12-9-21-26(16(12)6-15)18-7-17(24-14-4-5-14)27-19(25-18)13(8-20)10-22-27/h2-3,6-7,9-10,14,24H,4-5H2,1H3,(H,23,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human Erg |
ACS Med Chem Lett 3: 278-283 (2012)
Article DOI: 10.1021/ml200257n
BindingDB Entry DOI: 10.7270/Q23N24GS |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50388782
(CHEMBL2062564)Show SMILES CC(=O)Nc1ccc2cnn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 Show InChI InChI=1S/C19H16N8O/c1-11(28)23-15-3-2-12-9-21-26(16(12)6-15)18-7-17(24-14-4-5-14)27-19(25-18)13(8-20)10-22-27/h2-3,6-7,9-10,14,24H,4-5H2,1H3,(H,23,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 |
ACS Med Chem Lett 3: 278-283 (2012)
Article DOI: 10.1021/ml200257n
BindingDB Entry DOI: 10.7270/Q23N24GS |
More data for this
Ligand-Target Pair | |
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