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BDBM50388784 CHEMBL2062575

SMILES: CN(C)CCCNc1cc(nc2c(cnn12)C#N)-n1ccc2ccc(NC(C)=O)cc12

InChI Key: InChIKey=LGAQZKSRZOPELW-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50388784
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50388784 (CHEMBL2062575) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of GSK3beta				ACS Med Chem Lett 3: 278-283 (2012) Article DOI: 10.1021/ml200257n BindingDB Entry DOI: 10.7270/Q23N24GS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 2 (HIPK2) (Homo sapiens (Human))	BDBM50388784 (CHEMBL2062575) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HipK2				ACS Med Chem Lett 3: 278-283 (2012) Article DOI: 10.1021/ml200257n BindingDB Entry DOI: 10.7270/Q23N24GS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50388784 (CHEMBL2062575) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...				ACS Med Chem Lett 3: 278-283 (2012) Article DOI: 10.1021/ml200257n BindingDB Entry DOI: 10.7270/Q23N24GS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50388784 (CHEMBL2062575) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of CK2alpha in human HCT116 cells assessed as decrease in AKT phosphorylation at S129 residue after 3 to 24 hrs by Western blot analysis				ACS Med Chem Lett 3: 278-283 (2012) Article DOI: 10.1021/ml200257n BindingDB Entry DOI: 10.7270/Q23N24GS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50388784 (CHEMBL2062575) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of CDK2				ACS Med Chem Lett 3: 278-283 (2012) Article DOI: 10.1021/ml200257n BindingDB Entry DOI: 10.7270/Q23N24GS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair