BDBM50389007 CHEMBL1214255::US9321743, SD41

SMILES: O=C(N[C@H]1COC1=O)OCc1ccccc1

InChI Key: InChIKey=CWFZPRQDHIUBDO-VIFPVBQESA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (NAAA) (Rattus norvegicus (Rat))	BDBM50389007 (CHEMBL1214255 | US9321743, SD41) Show SMILES O=C(N[C@H]1COC1=O)OCc1ccccc1 |r| Show InChI InChI=1S/C11H11NO4/c13-10-9(7-15-10)12-11(14)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)/t9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	5.0	37
The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” US Patent					Assay Description Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...				US Patent US9321743 (2016) BindingDB Entry DOI: 10.7270/Q26D5RVT
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA) (Rattus norvegicus (Rat))	BDBM50389007 (CHEMBL1214255 | US9321743, SD41) Show SMILES O=C(N[C@H]1COC1=O)OCc1ccccc1 |r| Show InChI InChI=1S/C11H11NO4/c13-10-9(7-15-10)12-11(14)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)/t9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat NAAA				J Med Chem 63: 7475-7490 (2020)
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA) (Rattus norvegicus (Rat))	BDBM50389007 (CHEMBL1214255 | US9321743, SD41) Show SMILES O=C(N[C@H]1COC1=O)OCc1ccccc1 |r| Show InChI InChI=1S/C11H11NO4/c13-10-9(7-15-10)12-11(14)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)/t9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Carlo Bo Curated by ChEMBL					Assay Description Inhibition of rat recombinant NAAA expressed in HEK293 cells using heptadecenoylethanolamide as substrate after 30 mins by LC/MS analysis				J Med Chem 55: 4824-36 (2012) Article DOI: 10.1021/jm300349j BindingDB Entry DOI: 10.7270/Q20P113N
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA) (Rattus norvegicus (Rat))	BDBM50389007 (CHEMBL1214255 | US9321743, SD41) Show SMILES O=C(N[C@H]1COC1=O)OCc1ccccc1 |r| Show InChI InChI=1S/C11H11NO4/c13-10-9(7-15-10)12-11(14)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)/t9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat recombinant NAAA expressed in HEK293 cells after 30 mins				J Med Chem 53: 5770-81 (2010) Article DOI: 10.1021/jm100582w BindingDB Entry DOI: 10.7270/Q2X0689M
					More data for this Ligand-Target Pair