null

SMILES: CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccccc3F)[nH]nc2C1(C)C)c1ccccc1

InChI Key: InChIKey=GOMMKIIJNUTWRK-HXUWFJFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50389118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50389118 (CHEMBL2064563) Show SMILES CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccccc3F)[nH]nc2C1(C)C)c1ccccc1 |r| Show InChI InChI=1S/C25H29FN6O2/c1-25(2)21-18(22(30-29-21)28-23(33)17-12-8-9-13-19(17)26)14-32(25)24(34)27-20(15-31(3)4)16-10-6-5-7-11-16/h5-13,20H,14-15H2,1-4H3,(H,27,34)(H2,28,29,30,33)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PAK4				J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50389118 (CHEMBL2064563) Show SMILES CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccccc3F)[nH]nc2C1(C)C)c1ccccc1 |r| Show InChI InChI=1S/C25H29FN6O2/c1-25(2)21-18(22(30-29-21)28-23(33)17-12-8-9-13-19(17)26)14-32(25)24(34)27-20(15-31(3)4)16-10-6-5-7-11-16/h5-13,20H,14-15H2,1-4H3,(H,27,34)(H2,28,29,30,33)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assay				J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W
					More data for this Ligand-Target Pair