Found 4 hits for monomerid = 50389594 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50389594
(CHEMBL2069506)Show SMILES O=S1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26N4OS/c30-31-12-10-17(11-13-31)23-24-19(18-8-4-5-9-20(18)27-24)14-21(28-23)25-26-15-22(29-25)16-6-2-1-3-7-16/h1-9,15,17,21,23,27-28H,10-14H2,(H,26,29)/t17?,21-,23?,31?/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Antagonist activity at human SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated... |
ACS Med Chem Lett 3: 289-293 (2012)
Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50389594
(CHEMBL2069506)Show SMILES O=S1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26N4OS/c30-31-12-10-17(11-13-31)23-24-19(18-8-4-5-9-20(18)27-24)14-21(28-23)25-26-15-22(29-25)16-6-2-1-3-7-16/h1-9,15,17,21,23,27-28H,10-14H2,(H,26,29)/t17?,21-,23?,31?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of [35S]MK499 from human Erg expressed in HEK293 cells after 60 mins by scintillation counting |
ACS Med Chem Lett 3: 289-293 (2012)
Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH |
More data for this Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50389594
(CHEMBL2069506)Show SMILES O=S1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26N4OS/c30-31-12-10-17(11-13-31)23-24-19(18-8-4-5-9-20(18)27-24)14-21(28-23)25-26-15-22(29-25)16-6-2-1-3-7-16/h1-9,15,17,21,23,27-28H,10-14H2,(H,26,29)/t17?,21-,23?,31?/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation counting |
ACS Med Chem Lett 3: 289-293 (2012)
Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH |
More data for this Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50389594
(CHEMBL2069506)Show SMILES O=S1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26N4OS/c30-31-12-10-17(11-13-31)23-24-19(18-8-4-5-9-20(18)27-24)14-21(28-23)25-26-15-22(29-25)16-6-2-1-3-7-16/h1-9,15,17,21,23,27-28H,10-14H2,(H,26,29)/t17?,21-,23?,31?/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation counting |
ACS Med Chem Lett 3: 289-293 (2012)
Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH |
More data for this Ligand-Target Pair | |