BDBM50389601 CHEMBL2069513

SMILES: CNC(=O)N1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1

InChI Key: InChIKey=XHIMQCYKHSICAY-LETIRJCYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50389601 (CHEMBL2069513) Show SMILES CNC(=O)N1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C27H30N6O/c1-28-27(34)33-13-11-18(12-14-33)24-25-20(19-9-5-6-10-21(19)30-25)15-22(31-24)26-29-16-23(32-26)17-7-3-2-4-8-17/h2-10,16,18,22,24,30-31H,11-15H2,1H3,(H,28,34)(H,29,32)/t22-,24?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation counting				ACS Med Chem Lett 3: 289-293 (2012) Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50389601 (CHEMBL2069513) Show SMILES CNC(=O)N1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C27H30N6O/c1-28-27(34)33-13-11-18(12-14-33)24-25-20(19-9-5-6-10-21(19)30-25)15-22(31-24)26-29-16-23(32-26)17-7-3-2-4-8-17/h2-10,16,18,22,24,30-31H,11-15H2,1H3,(H,28,34)(H,29,32)/t22-,24?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human Erg expressed in HEK293 cells after 60 mins by scintillation counting				ACS Med Chem Lett 3: 289-293 (2012) Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50389601 (CHEMBL2069513) Show SMILES CNC(=O)N1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C27H30N6O/c1-28-27(34)33-13-11-18(12-14-33)24-25-20(19-9-5-6-10-21(19)30-25)15-22(31-24)26-29-16-23(32-26)17-7-3-2-4-8-17/h2-10,16,18,22,24,30-31H,11-15H2,1H3,(H,28,34)(H,29,32)/t22-,24?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated...				ACS Med Chem Lett 3: 289-293 (2012) Article DOI: 10.1021/ml200272z BindingDB Entry DOI: 10.7270/Q2K938MH
					More data for this Ligand-Target Pair