BDBM50389852 CHEMBL2070874

SMILES: Cc1[nH]c2ccccc2c1C(Nc1ccc(cc1)[N+]([O-])=O)c1ccccc1Cl

InChI Key: InChIKey=ACNLXCIXYZWHOW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50389852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50389852 (CHEMBL2070874) Show SMILES Cc1[nH]c2ccccc2c1C(Nc1ccc(cc1)[N+]([O-])=O)c1ccccc1Cl Show InChI InChI=1S/C22H18ClN3O2/c1-14-21(18-7-3-5-9-20(18)24-14)22(17-6-2-4-8-19(17)23)25-15-10-12-16(13-11-15)26(27)28/h2-13,22,24-25H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of CMV-VDR expressed in human HEK293T cells assessed as inhibition of 1,25-(OH)2D3-induced CYP24A1 promoter transcription after 16 hrs by ...				J Med Chem 55: 4640-51 (2012) Article DOI: 10.1021/jm300460c BindingDB Entry DOI: 10.7270/Q2HD7WRP
					More data for this Ligand-Target Pair