BDBM50389869 CHEMBL2070856

SMILES: COCC(=O)Oc1c(Sc2ccc(Cl)cc2)c(C)nn1-c1ccccc1

InChI Key: InChIKey=RAHUAHOXTWBZOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50389869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50389869 (CHEMBL2070856) Show SMILES COCC(=O)Oc1c(Sc2ccc(Cl)cc2)c(C)nn1-c1ccccc1 Show InChI InChI=1S/C19H17ClN2O3S/c1-13-18(26-16-10-8-14(20)9-11-16)19(25-17(23)12-24-2)22(21-13)15-6-4-3-5-7-15/h3-11H,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 after 3 hrs by fluorescence polarization assay				J Med Chem 55: 4640-51 (2012) Article DOI: 10.1021/jm300460c BindingDB Entry DOI: 10.7270/Q2HD7WRP
					More data for this Ligand-Target Pair