BDBM50390010 CHEMBL2071516

SMILES: OC1OC(=O)C(Br)=C1c1ccc(cc1)C(=O)Nc1ccccc1

InChI Key: InChIKey=KASJRDOUXBGAAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50390010 (CHEMBL2071516) Show SMILES OC1OC(=O)C(Br)=C1c1ccc(cc1)C(=O)Nc1ccccc1 |c:6| Show InChI InChI=1S/C17H12BrNO4/c18-14-13(16(21)23-17(14)22)10-6-8-11(9-7-10)15(20)19-12-4-2-1-3-5-12/h1-9,16,21H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Inhibition of mPGES-1-mediated PGE2 formation in IL-1beta-stimulated human A549 cells preincubated for 10 mins measured after 1 min by RP-HPLC analys...				Bioorg Med Chem 20: 5012-6 (2012) Article DOI: 10.1016/j.bmc.2012.06.032 BindingDB Entry DOI: 10.7270/Q2GF0VKD
					More data for this Ligand-Target Pair