BDBM50390143 CHEMBL2069686

SMILES: COC(C(=O)N\N=C\c1cc(OC)c(Br)c(OC)c1)c1cnc2ccccc2c1

InChI Key: InChIKey=PJGNBOMULNQAOJ-BHGWPJFGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390143 (CHEMBL2069686) Show SMILES COC(C(=O)N\N=C\c1cc(OC)c(Br)c(OC)c1)c1cnc2ccccc2c1 Show InChI InChI=1S/C21H20BrN3O4/c1-27-17-8-13(9-18(28-2)19(17)22)11-24-25-21(26)20(29-3)15-10-14-6-4-5-7-16(14)23-12-15/h4-12,20H,1-3H3,(H,25,26)/b24-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair