BDBM50390150 CHEMBL2069679

SMILES: COC(C(=O)N\N=C\c1cc(OC)c(Br)c(OC)c1)c1ccc(cc1)N1CCCC1

InChI Key: InChIKey=YZLBUJSLQHVHLJ-ZVHZXABRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390150 (CHEMBL2069679) Show SMILES COC(C(=O)N\N=C\c1cc(OC)c(Br)c(OC)c1)c1ccc(cc1)N1CCCC1 Show InChI InChI=1S/C22H26BrN3O4/c1-28-18-12-15(13-19(29-2)20(18)23)14-24-25-22(27)21(30-3)16-6-8-17(9-7-16)26-10-4-5-11-26/h6-9,12-14,21H,4-5,10-11H2,1-3H3,(H,25,27)/b24-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair