BDBM50390211 CHEMBL2070134

SMILES: COc1cnc(nc1NCc1ccc(F)cc1C(F)(F)F)-c1ccccn1

InChI Key: InChIKey=WZTXCIJAMBUMOO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390211 (CHEMBL2070134) Show SMILES COc1cnc(nc1NCc1ccc(F)cc1C(F)(F)F)-c1ccccn1 Show InChI InChI=1S/C18H14F4N4O/c1-27-15-10-25-16(14-4-2-3-7-23-14)26-17(15)24-9-11-5-6-12(19)8-13(11)18(20,21)22/h2-8,10H,9H2,1H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by Rb efflux assay				Bioorg Med Chem Lett 22: 5681-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.087 BindingDB Entry DOI: 10.7270/Q25X2B0C
					More data for this Ligand-Target Pair