BDBM50390459 CHEMBL2071591

SMILES: CC(C)C(NC(=O)OC(C)(C)C)C(=O)c1ccc(Cl)cn1

InChI Key: InChIKey=JYVPQGZHLMFNTN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50390459 (CHEMBL2071591) Show SMILES CC(C)C(NC(=O)OC(C)(C)C)C(=O)c1ccc(Cl)cn1 Show InChI InChI=1S/C15H21ClN2O3/c1-9(2)12(18-14(20)21-15(3,4)5)13(19)11-7-6-10(16)8-17-11/h6-9,12H,1-5H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Zn2+-induced intracellular calcium flux by FLIPR assay				Bioorg Med Chem Lett 22: 5485-92 (2012) Article DOI: 10.1016/j.bmcl.2012.07.032 BindingDB Entry DOI: 10.7270/Q2RR20B8
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50390459 (CHEMBL2071591) Show SMILES CC(C)C(NC(=O)OC(C)(C)C)C(=O)c1ccc(Cl)cn1 Show InChI InChI=1S/C15H21ClN2O3/c1-9(2)12(18-14(20)21-15(3,4)5)13(19)11-7-6-10(16)8-17-11/h6-9,12H,1-5H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Ca2+-induced intracellular calcium flux by FLIPR assay				Bioorg Med Chem Lett 22: 5485-92 (2012) Article DOI: 10.1016/j.bmcl.2012.07.032 BindingDB Entry DOI: 10.7270/Q2RR20B8
					More data for this Ligand-Target Pair