BDBM50390494 CHEMBL2071608

SMILES: N#Cc1ccc2nc(Nc3ccc(Oc4ccccc4)cc3)[nH]c2c1

InChI Key: InChIKey=HRMBUBFDDLZSRF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50390494 (CHEMBL2071608) Show SMILES N#Cc1ccc2nc(Nc3ccc(Oc4ccccc4)cc3)[nH]c2c1 Show InChI InChI=1S/C20H14N4O/c21-13-14-6-11-18-19(12-14)24-20(23-18)22-15-7-9-17(10-8-15)25-16-4-2-1-3-5-16/h1-12H,(H2,22,23,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CK1delta by Lance assay				Bioorg Med Chem Lett 22: 5392-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.046 BindingDB Entry DOI: 10.7270/Q2CF9R6Q
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Homo sapiens (Human))	BDBM50390494 (CHEMBL2071608) Show SMILES N#Cc1ccc2nc(Nc3ccc(Oc4ccccc4)cc3)[nH]c2c1 Show InChI InChI=1S/C20H14N4O/c21-13-14-6-11-18-19(12-14)24-20(23-18)22-15-7-9-17(10-8-15)25-16-4-2-1-3-5-16/h1-12H,(H2,22,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CK1alpha by Lance assay				Bioorg Med Chem Lett 22: 5392-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.046 BindingDB Entry DOI: 10.7270/Q2CF9R6Q
					More data for this Ligand-Target Pair