BDBM50390557 CHEMBL2069346

SMILES: FC(F)(F)c1ccnc(Nc2cccc(n2)-c2cccc(c2)N2CCNCC2)c1

InChI Key: InChIKey=FCPDILGNMHIWJE-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl-tRNA synthetase (Homo sapiens (Human))	BDBM50390557 (CHEMBL2069346) Show SMILES FC(F)(F)c1ccnc(Nc2cccc(n2)-c2cccc(c2)N2CCNCC2)c1 Show InChI InChI=1S/C21H20F3N5/c22-21(23,24)16-7-8-26-20(14-16)28-19-6-2-5-18(27-19)15-3-1-4-17(13-15)29-11-9-25-10-12-29/h1-8,13-14,25H,9-12H2,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assay				Bioorg Med Chem Lett 22: 5419-23 (2012) Article DOI: 10.1016/j.bmcl.2012.07.045 BindingDB Entry DOI: 10.7270/Q2416Z4V
					More data for this Ligand-Target Pair