BDBM50390572 CHEMBL2069361

SMILES: Cc1ccnc(Nc2cccc(n2)-c2cccnc2)c1

InChI Key: InChIKey=AAXCNJIPLAHVFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl-tRNA synthetase (Homo sapiens (Human))	BDBM50390572 (CHEMBL2069361) Show SMILES Cc1ccnc(Nc2cccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C16H14N4/c1-12-7-9-18-16(10-12)20-15-6-2-5-14(19-15)13-4-3-8-17-11-13/h2-11H,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assay				Bioorg Med Chem Lett 22: 5419-23 (2012) Article DOI: 10.1016/j.bmcl.2012.07.045 BindingDB Entry DOI: 10.7270/Q2416Z4V
					More data for this Ligand-Target Pair