BDBM50390722 CHEMBL2070345

SMILES: CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)C(F)(F)F)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=YCIQIRLTSAQVSK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390722 (CHEMBL2070345) Show SMILES CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H13F8NO3S/c1-26(30(28,29)13-5-3-2-4-6-13)12-9-7-11(8-10-12)14(27,16(20,21)22)15(18,19)17(23,24)25/h2-10,27H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair