BDBM50390736 CHEMBL2070359

SMILES: CC(C)CN(c1ccc(cc1)C(O)(C#CC1=CCCCC1)C(F)(F)F)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=NNEYGSCCUBHPHI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390736 (CHEMBL2070359) Show SMILES CC(C)CN(c1ccc(cc1)C(O)(C#CC1=CCCCC1)C(F)(F)F)S(=O)(=O)c1ccccc1 |t:16| Show InChI InChI=1S/C26H28F3NO3S/c1-20(2)19-30(34(32,33)24-11-7-4-8-12-24)23-15-13-22(14-16-23)25(31,26(27,28)29)18-17-21-9-5-3-6-10-21/h4,7-9,11-16,20,31H,3,5-6,10,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390736 (CHEMBL2070359) Show SMILES CC(C)CN(c1ccc(cc1)C(O)(C#CC1=CCCCC1)C(F)(F)F)S(=O)(=O)c1ccccc1 |t:16| Show InChI InChI=1S/C26H28F3NO3S/c1-20(2)19-30(34(32,33)24-11-7-4-8-12-24)23-15-13-22(14-16-23)25(31,26(27,28)29)18-17-21-9-5-3-6-10-21/h4,7-9,11-16,20,31H,3,5-6,10,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LXRbeta ligand binding domain expressed in HEK293 cells coexpressing GAL4 assessed as decrease in [3H]N-(4-(1,1,1,3,3,3-hexafl...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair