BDBM50390745 CHEMBL2070368

SMILES: CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=IPVOYRALYXDGRZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390745 (CHEMBL2070368) Show SMILES CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H23F6NO3S/c1-19(2)18-34(38(36,37)24-9-4-3-5-10-24)23-13-11-21(12-14-23)25(35,27(31,32)33)16-15-20-7-6-8-22(17-20)26(28,29)30/h3-14,17,19,35H,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390745 (CHEMBL2070368) Show SMILES CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H23F6NO3S/c1-19(2)18-34(38(36,37)24-9-4-3-5-10-24)23-13-11-21(12-14-23)25(35,27(31,32)33)16-15-20-7-6-8-22(17-20)26(28,29)30/h3-14,17,19,35H,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LXRbeta ligand binding domain expressed in HEK293 cells coexpressing GAL4 assessed as decrease in [3H]N-(4-(1,1,1,3,3,3-hexafl...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair