Found 4 hits for monomerid = 50390787 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
LIM domain kinase 1
(Homo sapiens (Human)) | BDBM50390787
(CHEMBL2070611)Show SMILES CCC(CC)Oc1cc(C)c(c(C)c1)-c1cc(nc(n1)-c1cnccn1)-c1cnc(NC(C)=O)s1 Show InChI InChI=1S/C26H28N6O2S/c1-6-18(7-2)34-19-10-15(3)24(16(4)11-19)21-12-20(23-14-29-26(35-23)30-17(5)33)31-25(32-21)22-13-27-8-9-28-22/h8-14,18H,6-7H2,1-5H3,(H,29,30,33) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Inhibition of LIMK1 |
Bioorg Med Chem Lett 22: 5995-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.002 BindingDB Entry DOI: 10.7270/Q2K075CJ |
More data for this Ligand-Target Pair | |
Dual specificity testis-specific protein kinase 2
(Homo sapiens (Human)) | BDBM50390787
(CHEMBL2070611)Show SMILES CCC(CC)Oc1cc(C)c(c(C)c1)-c1cc(nc(n1)-c1cnccn1)-c1cnc(NC(C)=O)s1 Show InChI InChI=1S/C26H28N6O2S/c1-6-18(7-2)34-19-10-15(3)24(16(4)11-19)21-12-20(23-14-29-26(35-23)30-17(5)33)31-25(32-21)22-13-27-8-9-28-22/h8-14,18H,6-7H2,1-5H3,(H,29,30,33) | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Inhibition of TESK2 |
Bioorg Med Chem Lett 22: 5995-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.002 BindingDB Entry DOI: 10.7270/Q2K075CJ |
More data for this Ligand-Target Pair | |
Dual specificity testis-specific protein kinase 1
(Homo sapiens (Human)) | BDBM50390787
(CHEMBL2070611)Show SMILES CCC(CC)Oc1cc(C)c(c(C)c1)-c1cc(nc(n1)-c1cnccn1)-c1cnc(NC(C)=O)s1 Show InChI InChI=1S/C26H28N6O2S/c1-6-18(7-2)34-19-10-15(3)24(16(4)11-19)21-12-20(23-14-29-26(35-23)30-17(5)33)31-25(32-21)22-13-27-8-9-28-22/h8-14,18H,6-7H2,1-5H3,(H,29,30,33) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Inhibition of TESK1 |
Bioorg Med Chem Lett 22: 5995-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.002 BindingDB Entry DOI: 10.7270/Q2K075CJ |
More data for this Ligand-Target Pair | |
LIM domain kinase 2
(Homo sapiens (Human)) | BDBM50390787
(CHEMBL2070611)Show SMILES CCC(CC)Oc1cc(C)c(c(C)c1)-c1cc(nc(n1)-c1cnccn1)-c1cnc(NC(C)=O)s1 Show InChI InChI=1S/C26H28N6O2S/c1-6-18(7-2)34-19-10-15(3)24(16(4)11-19)21-12-20(23-14-29-26(35-23)30-17(5)33)31-25(32-21)22-13-27-8-9-28-22/h8-14,18H,6-7H2,1-5H3,(H,29,30,33) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Inhibition of LIMK2 |
Bioorg Med Chem Lett 22: 5995-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.002 BindingDB Entry DOI: 10.7270/Q2K075CJ |
More data for this Ligand-Target Pair | |