BDBM50390880 CHEMBL2070972

SMILES: COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(F)cc2Cl)n1

InChI Key: InChIKey=ZIYSRDSGXNYWPE-LJQANCHMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50390880 (CHEMBL2070972) Show SMILES COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(F)cc2Cl)n1 |r| Show InChI InChI=1S/C22H21ClFN3O4S2/c1-31-16-8-5-14(6-9-16)18-13-32-22(25-18)26-21(28)19-4-2-3-11-27(19)33(29,30)20-10-7-15(24)12-17(20)23/h5-10,12-13,19H,2-4,11H2,1H3,(H,25,26,28)/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay				Bioorg Med Chem Lett 22: 5936-41 (2012) Article DOI: 10.1016/j.bmcl.2012.07.060 BindingDB Entry DOI: 10.7270/Q25T3MKN
					More data for this Ligand-Target Pair