BDBM50391002 CHEMBL2074599
SMILES: CNc1nc2c(Cc3cccnc3)c(C)c(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)c(C)c2s1
InChI Key: InChIKey=RJBKVKVYNJTHJS-DQSYDGHTSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Canalicular multispecific organic anion transporter 2 (Rattus norvegicus) | BDBM50391002 (CHEMBL2074599) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cells | Pharm Res 19: 34-41 (2002) BindingDB Entry DOI: 10.7270/Q2G44RCW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Canalicular multispecific organic anion transporter 1 (Rattus norvegicus) | BDBM50391002 (CHEMBL2074599) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | PubMed | 3.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tokyo Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of DNP-SG uptake in bile canalicular membrane vesicles from SD rat | J Pharmacol Exp Ther 282: 866-72 (1997) BindingDB Entry DOI: 10.7270/Q2PV6P74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance associated protein (Homo sapiens (Human)) | BDBM50391002 (CHEMBL2074599) | UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | PubMed | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cells | Pharm Res 19: 34-41 (2002) BindingDB Entry DOI: 10.7270/Q2G44RCW | |||||||||||
More data for this Ligand-Target Pair |