BDBM50391042 CHEMBL2088408

SMILES: CC(C)(C)c1ccc(cc1)C(=O)Nc1ccc2sc(CN)nc2c1

InChI Key: InChIKey=MHAZVCNABBNQFF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50391042 (CHEMBL2088408) Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1ccc2sc(CN)nc2c1 Show InChI InChI=1S/C19H21N3OS/c1-19(2,3)13-6-4-12(5-7-13)18(23)21-14-8-9-16-15(10-14)22-17(11-20)24-16/h4-10H,11,20H2,1-3H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	987	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPV1 receptor assessed as inhibition of capsaicin-induced calcium uptake by FLIPR assay				Bioorg Med Chem Lett 22: 6205-11 (2012) Article DOI: 10.1016/j.bmcl.2012.08.018 BindingDB Entry DOI: 10.7270/Q29C6ZGB
					More data for this Ligand-Target Pair