BDBM50391634 CHEMBL2148012

SMILES: Cc1ccc(cc1)C(=O)N[C@@H](Cc1ccc(OCCc2ccccc2)cc1)C(=O)NO

InChI Key: InChIKey=CSMSDQFQJKDBEB-QHCPKHFHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50391634 (CHEMBL2148012) Show SMILES Cc1ccc(cc1)C(=O)N[C@@H](Cc1ccc(OCCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C25H26N2O4/c1-18-7-11-21(12-8-18)24(28)26-23(25(29)27-30)17-20-9-13-22(14-10-20)31-16-15-19-5-3-2-4-6-19/h2-14,23,30H,15-17H2,1H3,(H,26,28)(H,27,29)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of HDAC8 after 45 mins by microplate fluorometric analysis				Bioorg Med Chem 20: 5738-44 (2012) Article DOI: 10.1016/j.bmc.2012.08.014 BindingDB Entry DOI: 10.7270/Q2988849
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50391634 (CHEMBL2148012) Show SMILES Cc1ccc(cc1)C(=O)N[C@@H](Cc1ccc(OCCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C25H26N2O4/c1-18-7-11-21(12-8-18)24(28)26-23(25(29)27-30)17-20-9-13-22(14-10-20)31-16-15-19-5-3-2-4-6-19/h2-14,23,30H,15-17H2,1H3,(H,26,28)(H,27,29)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of MMP2 using BML-P125-9090 as substrate after 30 mins by microplate reader analysis				Bioorg Med Chem 20: 5738-44 (2012) Article DOI: 10.1016/j.bmc.2012.08.014 BindingDB Entry DOI: 10.7270/Q2988849
					More data for this Ligand-Target Pair