BDBM50391910 CHEMBL2147550
SMILES: CC(C)(N)CNc1nc(cc2cnccc12)-c1ccncc1F
InChI Key: InChIKey=DVMQYKHCZLPSAP-UHFFFAOYSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50391910 (CHEMBL2147550) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCalpha assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, eta (Homo sapiens (Human)) | BDBM50391910 (CHEMBL2147550) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCeta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity ass... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50391910 (CHEMBL2147550) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCtheta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50391910 (CHEMBL2147550) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCdelta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, epsilon (Homo sapiens (Human)) | BDBM50391910 (CHEMBL2147550) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCepsilon assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PKC alpha and beta-2 (Homo sapiens (Human)) | BDBM50391910 (CHEMBL2147550) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 961 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCbeta1 assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair |