BDBM50391937 CHEMBL2147759

SMILES: Oc1ccc2C(=O)\C(Oc2c1CN1CCCNCC1)=C\c1c[nH]c2ccccc12

InChI Key: InChIKey=SYXGRVJAKXGVFV-MTJSOVHGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50391937 (CHEMBL2147759) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCCNCC1)=C\c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H23N3O3/c27-20-7-6-17-22(28)21(12-15-13-25-19-5-2-1-4-16(15)19)29-23(17)18(20)14-26-10-3-8-24-9-11-26/h1-2,4-7,12-13,24-25,27H,3,8-11,14H2/b21-12-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				J Med Chem 55: 5151-64 (2012) Article DOI: 10.1021/jm3001289 BindingDB Entry DOI: 10.7270/Q2PC33G8
					More data for this Ligand-Target Pair