BDBM50391939 CHEMBL2147760

SMILES: Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2ccccc12

InChI Key: InChIKey=MDAJELCLWMJVCO-JAIQZWGSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50391939 (CHEMBL2147760) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2ccccc12 Show InChI InChI=1S/C22H21N3O3/c26-19-6-5-16-21(27)20(11-14-12-24-18-4-2-1-3-15(14)18)28-22(16)17(19)13-25-9-7-23-8-10-25/h1-6,11-12,23-24,26H,7-10,13H2/b20-11-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				J Med Chem 55: 5151-64 (2012) Article DOI: 10.1021/jm3001289 BindingDB Entry DOI: 10.7270/Q2PC33G8
					More data for this Ligand-Target Pair