BDBM50391943 CHEMBL2147766

SMILES: O=C1\C(Oc2c1ccc(OCc1ccccc1)c2CN1CCNCC1)=C\c1c[nH]c2ccccc12

InChI Key: InChIKey=WPCAFUUVDWYWAL-YUMHPJSZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50391943 (CHEMBL2147766) Show SMILES O=C1\C(Oc2c1ccc(OCc1ccccc1)c2CN1CCNCC1)=C\c1c[nH]c2ccccc12 Show InChI InChI=1S/C29H27N3O3/c33-28-23-10-11-26(34-19-20-6-2-1-3-7-20)24(18-32-14-12-30-13-15-32)29(23)35-27(28)16-21-17-31-25-9-5-4-8-22(21)25/h1-11,16-17,30-31H,12-15,18-19H2/b27-16-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				J Med Chem 55: 5151-64 (2012) Article DOI: 10.1021/jm3001289 BindingDB Entry DOI: 10.7270/Q2PC33G8
					More data for this Ligand-Target Pair