null
SMILES: Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C#N
InChI Key: InChIKey=WELBHFQHGYVGJA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM50391959 (CHEMBL2152268) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a |
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL | Assay Description Binding affinity to PI3Kalpha by high throughput assay | J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50391959 (CHEMBL2152268) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL | Assay Description Binding affinity to TRKA by high throughput assay | J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3 | |||||||||||
More data for this Ligand-Target Pair |