null

SMILES: Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C#N

InChI Key: InChIKey=WELBHFQHGYVGJA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50391959 (CHEMBL2152268) Show SMILES Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C#N Show InChI InChI=1S/C20H14N4/c21-10-13-3-1-4-14(7-13)16-9-18-19(12-24-20(18)23-11-16)15-5-2-6-17(22)8-15/h1-9,11-12H,22H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Binding affinity to PI3Kalpha by high throughput assay				J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50391959 (CHEMBL2152268) Show SMILES Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C#N Show InChI InChI=1S/C20H14N4/c21-10-13-3-1-4-14(7-13)16-9-18-19(12-24-20(18)23-11-16)15-5-2-6-17(22)8-15/h1-9,11-12H,22H2,(H,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Binding affinity to TRKA by high throughput assay				J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3
					More data for this Ligand-Target Pair