BDBM50392071 CHEMBL2152575

SMILES: CC(C)(C)c1ccc(Nc2ccccc2C(N)=O)cc1

InChI Key: InChIKey=ZAPWXBHWJPRCJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50392071 (CHEMBL2152575) Show SMILES CC(C)(C)c1ccc(Nc2ccccc2C(N)=O)cc1 Show InChI InChI=1S/C17H20N2O/c1-17(2,3)12-8-10-13(11-9-12)19-15-7-5-4-6-14(15)16(18)20/h4-11,19H,1-3H3,(H2,18,20)	PDB MMDB NCI pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair